hahaha. i opened up old files to look for things to delete and found this. the main point is the very end, so skip til there since the rest isn't so important. copied and pasted below w/in the dashed lines: --------------------------- - immediate resistance w/ antibody - cell-mediate – antigen specific t cells, have to recall, not immediate o cytotoxic t cells o recognize and kill selves - vaccine for tb o BCG o RD-1 missing in gene § Encodes for secretion system, important for cytokine response o Aren’t given BCG in U.S. § Tuberculin test (PPD) § Based on T cells that have seen TB § + à 6-9 mos of antibiotics § convert to PPD positive, lose capacity of testing - strep staph o antibodies BCG/listeria - innate immunity - after 6 mos innate back to normal - take 60 mice give them listeria - day 6 , take 15 of em, challenge them 5 w/ listerika, salm, bcg - then sacrifice and analyze - let them sit for 6 mos - challenge - reistant to listeria and not to the others Listeria/ LLO - why can’t just infect another mphage - the 1st cell to come in in infection is neutrophil - bugs released and gobble up - make mouse meutropenic, do well in absence of neutrophils?? - Cytotoxic strains are avirulent?? 13.a. how can tb be … streptomyocin だめ。(_ _*) --------------------------- lollll.. what the heck? it reads "da-me". meaning "no good" in japanese. i totally cracked up. |